SCHEMBL25752363

SCHEMBL25752363

CC(C)c1cc2c(=O)c3cc4c(cc3n(-c3ccccc3)c2cc1C(C)C)c(=O)c1cc(C(C)C)c(C(C)C)cc1n4-c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 3/20 0.42
GSK3B P49841 3/20 0.42
KDM4E B2RXH2 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ATM Q13315 1/20 0.40
MAT2A P31153 6/20 0.40
GAA P10253 2/20 0.39
MAPK1 P28482 1/20 0.38
PGR P06401 2/20 0.37
FAAH O00519 1/20 0.37
MGLL Q99685 1/20 0.37
POLB P06746 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PRMT5 O14744 1/20 0.35
MAPK8 P45983 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752389 0.86 MGLL (0.45) KDM4EL3MBTL1MAT2AMGLLPOLB
SCHEMBL25752377 0.86 MGLL (0.37) GSK3AGSK3BKDM4EGAAMAPK1
SCHEMBL25752399 0.82 NR1H4 (0.37) MAPK1CYP2C9NPSR1ALDH1A1
SCHEMBL25752365 0.81 MAT2A (0.50) GSK3AGSK3BKDM4EL3MBTL1ATM
SCHEMBL25752552 0.81 FABP3 (0.33) MGLL
SCHEMBL25752413 0.81 HSP90AA1 (0.38) KDM4EFAAHMGLLCYP1A2CYP2C9
SCHEMBL25752359 0.78 KDM4E (0.44) GSK3AGSK3BKDM4EL3MBTL1ATM
SCHEMBL85788 0.78 KDM4E (0.63) GSK3AGSK3BKDM4EL3MBTL1ATM
SCHEMBL29416587 0.78 KDM4E (0.63) GSK3AGSK3BKDM4EL3MBTL1ATM
SCHEMBL25752328 0.75 ATM (0.39) L3MBTL1ATMGAAFAAHMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed