SCHEMBL25752365

SCHEMBL25752365

CC(C)c1ccc2c(=O)c3cc4c(cc3n(-c3ccccc3)c2c1)c(=O)c1ccc(C(C)C)cc1n4-c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 6/20 0.50
KDM4E B2RXH2 2/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
AKR1B1 P15121 1/20 0.38
KIF11 P52732 1/20 0.37
MAPK8 P45983 2/20 0.37
RORA P35398 1/20 0.36
RORC P51449 1/20 0.36
RORB Q92753 1/20 0.36
PRMT5 O14744 1/20 0.36
ALDH1A1 P00352 1/20 0.36
RECQL P46063 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
NOTUM Q6P988 1/20 0.36
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752390 0.91 MGLL (0.42) MAT2AKDM4EL3MBTL1MAPK8ALDH1A1
SCHEMBL20647203 0.87 MAT2A (0.50) MAT2AKDM4EATML3MBTL1KIF11
SCHEMBL25752378 0.87 TDP1 (0.39) MAT2AKDM4EL3MBTL1MAPK8ALDH1A1
SCHEMBL25752433 0.86 MAT2A (0.36) MAT2AKDM4EATML3MBTL1KIF11
SCHEMBL25752384 0.85 PTGS2 (0.42) MAT2AKDM4EATML3MBTL1RORA
SCHEMBL25752415 0.84 MAT2A (0.35) MAT2AKDM4EL3MBTL1MAPK8RORA
SCHEMBL1102445 0.83 KDM4E (0.56) MAT2AKDM4EATML3MBTL1KIF11
SCHEMBL25752400 0.83 PPARG (0.44) MAT2AKDM4EL3MBTL1MAPK8ALDH1A1
SCHEMBL9916263 0.83 KDM4E (0.60) MAT2AKDM4EATML3MBTL1KIF11
SCHEMBL25752363 0.81 GSK3A (0.42) MAT2AKDM4EATML3MBTL1MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed