SCHEMBL25752366

SCHEMBL25752366

CCc1ccc2c(=O)c3cc4c(cc3n(-c3ccccc3)c2c1)c(=O)c1ccc(CC)cc1n4-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 5/20 0.45
MAPK8 P45983 5/20 0.43
MAPK9 P45984 4/20 0.43
ALDH1A1 P00352 2/20 0.40
MGLL Q99685 1/20 0.40
PGR P06401 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PRMT5 O14744 1/20 0.39
CYP1A2 P05177 1/20 0.39
P2RX4 Q99571 2/20 0.38
RORA P35398 1/20 0.38
RORC P51449 1/20 0.38
RORB Q92753 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13226090 0.88 PGR (0.46) MAT2AMAPK8MAPK9ALDH1A1MGLL
SCHEMBL25752380 0.87 P2RX4 (0.43) ALDH1A1MGLLL3MBTL1NPC1LMNA
SCHEMBL8086611 0.87 KDM4E (0.49) MAPK8MAPK9ALDH1A1PGRL3MBTL1
SCHEMBL25752547 0.84 MAPT (0.38) ALDH1A1MGLLPGRL3MBTL1NPC1
SCHEMBL25752391 0.83 MAPT (0.40) MAT2AMAPK8MAPK9ALDH1A1MGLL
SCHEMBL25752401 0.83 MAPK8 (0.38) MAPK8MAPK9ALDH1A1MGLLPGR
SCHEMBL25752368 0.83 MAT2A (0.45) MAT2AMAPK8MAPK9ALDH1A1PGR
SCHEMBL17017083 0.83 KDM4E (0.60) MAT2AMAPK8MAPK9ALDH1A1PGR
SCHEMBL25752449 0.80 PGR (0.33) MAPK8ALDH1A1MGLLPGRRORA
SCHEMBL25752435 0.80 MAPT (0.36) ALDH1A1MGLLPGRL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed