SCHEMBL25752401

SCHEMBL25752401

CCc1ccc2c(=O)c3cc4c(cc3n(-c3ccc(C(C)(C)C)cc3)c2c1)c(=O)c1ccc(CC)cc1n4-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 2/20 0.38
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
POLB P06746 2/20 0.36
NR1H4 Q96RI1 3/20 0.35
PPARG P37231 2/20 0.35
PTGES O14684 1/20 0.34
MGLL Q99685 1/20 0.33
METAP2 P50579 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
DRD4 P21917 1/20 0.33
PGR P06401 2/20 0.33
RORA P35398 2/20 0.33
RORC P51449 2/20 0.33
RORB Q92753 2/20 0.33
DAO P14920 1/20 0.33
PMM2 O15305 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752449 0.89 PGR (0.33) MAPK8POLBMGLLALDH1A1PGR
SCHEMBL25752397 0.86 NR1H4 (0.40) MAPK8CYP2C9CYP2C19NR1H4PPARG
SCHEMBL25752404 0.85 NR1H4 (0.39) MAPK8CYP2C9CYP2C19NR1H4PPARG
SCHEMBL25752380 0.85 P2RX4 (0.43) CYP2C9CYP2C19POLBMGLLALDH1A1
SCHEMBL25752366 0.83 MAT2A (0.45) MAPK8MGLLALDH1A1MAPTMAPK1
SCHEMBL25752490 0.83 PGR (0.32) MAPK8PGRRORARORCRORB
SCHEMBL24605119 0.82 PPARG (0.43) MAPK8POLBPPARGMETAP2ALDH1A1
SCHEMBL25752394 0.82 NR1H4 (0.40) MAPK8CYP2C9CYP2C19NR1H4PPARG
SCHEMBL25752391 0.81 MAPT (0.40) MAPK8MGLLALDH1A1MAPTMAPK9
SCHEMBL13311194 0.80 PPARG (0.46) MAPK8CYP2C19NR1H4PPARGALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed