SCHEMBL25752449

SCHEMBL25752449

CCc1ccc2c(=O)c3cc4c(cc3n(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)c2c1)c(=O)c1ccc(CC)cc1n4-c1cc(C(C)(C)C)cc(C(C)(C)C)c1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.33
RORA P35398 1/20 0.33
RORC P51449 1/20 0.33
RORB Q92753 1/20 0.33
MAPK8 P45983 1/20 0.32
RXRA P19793 2/20 0.32
RXRB P28702 2/20 0.32
RXRG P48443 2/20 0.32
PSEN1 P49768 1/20 0.32
PSEN2 P49810 1/20 0.32
APH1B Q8WW43 1/20 0.32
NCSTN Q92542 1/20 0.32
APH1A Q96BI3 1/20 0.32
PSENEN Q9NZ42 1/20 0.32
POLB P06746 2/20 0.31
MGLL Q99685 2/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752401 0.89 MAPK8 (0.38) PGRRORARORCRORBMAPK8
SCHEMBL25752490 0.85 PGR (0.32) PGRRORARORCRORBMAPK8
SCHEMBL22960147 0.84 CA9 (0.34) PGRRORARORCRORBMAPK8
SCHEMBL25752451 0.83
SCHEMBL25752439 0.82 TSHR (0.32) MAPK8POLBALDH1A1
SCHEMBL25752547 0.82 MAPT (0.38) PGRRORARORCRORBMGLL
SCHEMBL25752366 0.80 MAT2A (0.45) PGRRORARORCRORBMAPK8
SCHEMBL25752554 0.80 ALDH1A1 (0.40) PGRRORARORCRORBMAPK8
SCHEMBL25752380 0.79 P2RX4 (0.43) POLBMGLLALDH1A1
SCHEMBL25752440 0.77 POLB (0.32) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed