SCHEMBL25752374

SCHEMBL25752374

Cc1ccc(-n2c3cc(C(C)(C)C)ccc3c(=O)c3cc4c(cc32)c(=O)c2ccc(C(C)(C)C)cc2n4-c2ccc(C)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.40
CA9 Q16790 3/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
NR1H4 Q96RI1 3/20 0.38
CA2 P00918 1/20 0.37
HTT P42858 1/20 0.36
HSD11B1 P28845 1/20 0.35
ALDH1A1 P00352 4/20 0.35
MAPT P10636 3/20 0.35
MAPK1 P28482 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
KDM4E B2RXH2 2/20 0.35
LMNA P02545 2/20 0.35
HPGD P15428 2/20 0.35
TP53 P04637 1/20 0.35
KMT2A Q03164 1/20 0.35
GLA P06280 1/20 0.34
GAA P10253 1/20 0.34
RUNX1 Q01196 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752397 0.92 NR1H4 (0.40) CA9CA12CA1NR1H4CA2
SCHEMBL25752394 0.91 NR1H4 (0.40) TSHRNR1H4HTTHSD11B1ALDH1A1
SCHEMBL25752411 0.88 MAPT (0.33) TSHRCA9CA12CA1NR1H4
SCHEMBL13053156 0.88 TSHR (0.48) TSHRCA9CA12CA1NR1H4
SCHEMBL25752361 0.87 MAT2A (0.45) CA9CA12CA1ALDH1A1MAPT
SCHEMBL22960147 0.85 CA9 (0.34) CA9CA12CA1NR1H4CA2
SCHEMBL25752387 0.85 PPARG (0.41) CA9CA12CA1NR1H4CA2
SCHEMBL25752370 0.84 HTT (0.41) TSHRCA9CA12CA1HTT
SCHEMBL25752439 0.82 TSHR (0.32) TSHRHTTALDH1A1MAPTMAPK1
SCHEMBL25752376 0.82 ALDH1A1 (0.36) TSHRHTTALDH1A1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed