SCHEMBL25752394

SCHEMBL25752394

Cc1ccc2c(=O)c3cc4c(cc3n(-c3ccc(C(C)(C)C)cc3)c2c1)c(=O)c1ccc(C)cc1n4-c1ccc(C(C)(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 4/20 0.40
TSHR P16473 1/20 0.40
MAPT P10636 2/20 0.37
ALDH1A1 P00352 1/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CCR9 P51686 1/20 0.37
RXRA P19793 1/20 0.36
MAPK8 P45983 1/20 0.36
HSD11B1 P28845 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
BCL2 P10415 1/20 0.35
MDM2 Q00987 1/20 0.35
MCL1 Q07820 1/20 0.35
PMM2 O15305 1/20 0.35
MPI P34949 1/20 0.35
PHOSPHO1 Q8TCT1 1/20 0.35
PPARG P37231 4/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25752374 0.91 TSHR (0.40) NR1H4TSHRMAPTALDH1A1MAPK1
SCHEMBL25752397 0.89 NR1H4 (0.40) NR1H4MAPTALDH1A1MAPK1NPSR1
SCHEMBL25752439 0.88 TSHR (0.32) TSHRMAPTALDH1A1MAPK1NPSR1
SCHEMBL25752370 0.88 HTT (0.41) TSHRMAPTALDH1A1MAPK1NPSR1
SCHEMBL25752396 0.85 NR1H4 (0.46) NR1H4TSHRMAPTALDH1A1MAPK1
SCHEMBL13311194 0.84 PPARG (0.46) NR1H4MAPTALDH1A1MAPK1NPSR1
SCHEMBL25752411 0.82 MAPT (0.33) NR1H4TSHRMAPTALDH1A1MAPK1
SCHEMBL25752398 0.82 NR1H4 (0.39) NR1H4TSHRMAPTALDH1A1MAPK1
SCHEMBL25752401 0.82 MAPK8 (0.38) NR1H4MAPTALDH1A1MAPK1NPSR1
SCHEMBL25752358 0.81 MAT2A (0.44) ALDH1A1MAPK1HTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209987-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed
US-20230209988-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DISPLAY DEVICE HAVING THE SAME LG DISPLAY CO., LTD. (KR) 2023-06-29 US disclosed