SCHEMBL25752681

SCHEMBL25752681

CC(C)(C)[Si](C)(C)OCC1OC(n2cnc3c(N=[N+]=[N-])ncnc32)CC1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.37
P2RY1 P47900 2/20 0.37
POLB P06746 1/20 0.35
ENPP1 P22413 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21011208 0.89 HIF1A (0.38) HIF1AP2RY1POLBENPP1
SCHEMBL7209817 0.88 HIF1A (0.39) HIF1AP2RY1POLBENPP1
SCHEMBL11986893 0.83 POLB (0.47) P2RY1POLBENPP1
SCHEMBL21317437 0.83 POLB (0.47) P2RY1POLBENPP1
SCHEMBL30944277 0.83 HIF1A (0.40) HIF1AP2RY1POLBENPP1
SCHEMBL7215063 0.83 POLB (0.47) P2RY1POLBENPP1
SCHEMBL30197148 0.83 POLB (0.47) P2RY1POLBENPP1
SCHEMBL1140779 0.83 HIF1A (0.42) HIF1AP2RY1POLBENPP1
SCHEMBL16459780 0.82 AHCY (0.38) HIF1AP2RY1
SCHEMBL30944273 0.81 HIF1A (0.39) HIF1AP2RY1POLBENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230175030-A1 NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES Nuclera Nucleics Ltd. (GB) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230175030-A1 NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES RNGTT, POLM, POLRMT HIF1A 2566/4885P2RY1 4351/4885POLB 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.