SCHEMBL25752747

SCHEMBL25752747

OC[C@H]1O[C@@H](n2ccc3c(O)ncnc32)CC1O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.53
ADK P55263 1/20 0.48
SLC29A1 Q99808 1/20 0.46
PIM1 P11309 1/20 0.46
CSNK2A2 P19784 1/20 0.46
CSNK2B P67870 1/20 0.46
CSNK2A1 P68400 1/20 0.46
CSNK2A3 Q8NEV1 1/20 0.46
ADRB1 P08588 1/20 0.46
DNMT1 P26358 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29398412 1.00 HIF1A (0.53) HIF1AADKSLC29A1PIM1CSNK2A2
SCHEMBL13771420 0.89 HIF1A (0.52) HIF1AADKSLC29A1PIM1CSNK2A2
2'-Deoxytubercidin SCHEMBL7872096 0.87 METTL3 (0.57) HIF1AADKADRB1DNMT1
2'-Deoxytubercidin SCHEMBL14294692 0.87 METTL3 (0.57) HIF1AADKADRB1DNMT1
2'-Deoxytubercidin SCHEMBL5918830 0.87 METTL3 (0.57) HIF1AADKADRB1DNMT1
2'-Deoxytubercidin SCHEMBL23982321 0.87 METTL3 (0.57) HIF1AADKADRB1DNMT1
2'-Deoxytubercidin SCHEMBL23982116 0.87 METTL3 (0.57) HIF1AADKADRB1DNMT1
2'-Deoxytubercidin SCHEMBL3229680 0.87 METTL3 (0.57) HIF1AADKADRB1DNMT1
SCHEMBL20691354 0.87 HIF1A (0.52) HIF1AADKSLC29A1PIM1CSNK2A2
2'-Deoxytubercidin SCHEMBL14104716 0.87 METTL3 (0.57) HIF1AADKADRB1DNMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230175030-A1 NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES Nuclera Nucleics Ltd. (GB) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230175030-A1 NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES RNGTT, POLM, POLRMT HIF1A 2566/4885ADK 1146/4885SLC29A1 850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.