Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | TK1 | P04183 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25752677 | 0.87 | TK1 (0.37) | ABCG2ABCB1TK1LMNATSHR | |
| SCHEMBL25752674 | 0.83 | POLB (0.51) | TK1 | |
| SCHEMBL25492657 | 0.80 | ALB (0.42) | TOP2AALB | |
| SCHEMBL25752765 | 0.79 | TOP2A (0.60) | TOP2ATK1 | |
| SCHEMBL23734184 | 0.78 | TOP2A (0.33) | TOP2A | |
| SCHEMBL24823749 | 0.78 | TOP2A (0.33) | TOP2A | |
| SCHEMBL21011208 | 0.78 | HIF1A (0.38) | — | |
| SCHEMBL24823007 | 0.74 | TOP2A (0.49) | TOP2ATK1 | |
| SCHEMBL23734351 | 0.74 | TOP2A (0.49) | TOP2ATK1 | |
| SCHEMBL25492550 | 0.74 | TOP2A (0.49) | TOP2ATK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230175030-A1 | NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES | Nuclera Nucleics Ltd. (GB) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230175030-A1 | NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES | RNGTT, POLM, POLRMT | TOP2A 136/4885ABCG2 3158/4885ABCB1 3074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.