Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | POLA1 | P09884 | 1/20 | 0.51 |
| ▸ | POLD1 | P28340 | 1/20 | 0.51 |
| ▸ | P2RY2 | P41231 | 9/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.42 |
| ▸ | POLG | P54098 | 2/20 | 0.41 |
| ▸ | TK1 | P04183 | 2/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22340128 | 0.90 | POLB (0.53) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL25752673 | 0.90 | POLB (0.53) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL25752770 | 0.87 | POLG (0.50) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL25752677 | 0.85 | TK1 (0.37) | POLBPOLA1POLD1TK1 | |
| SCHEMBL25752773 | 0.83 | TOP2A (0.39) | TK1 | |
| SCHEMBL25492567 | 0.82 | POLG (0.62) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL25492013 | 0.82 | POLG (0.62) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL25492066 | 0.82 | POLG (0.62) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL21011356 | 0.81 | P2RX3 (0.45) | POLBP2RY2 | |
| SCHEMBL23635762 | 0.80 | POLB (0.69) | POLBPOLA1POLD1P2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230175030-A1 | NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES | Nuclera Nucleics Ltd. (GB) | 2023-06-08 | — | — | US | disclosed |
| US-20230175030-A1 | NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES | Nuclera Nucleics Ltd. (GB) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230175030-A1 | NUCLEIC ACID POLYMER WITH AMINE-MASKED BASES | RNGTT, POLM, POLRMT | POLB 5/4885POLA1 21/4885POLD1 52/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.