SCHEMBL25752894

SCHEMBL25752894

CCc1ccc(OC)cc1S(=O)(=O)O

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 1/20 0.43
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
POLB P06746 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.40
MTNR1A P48039 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1607332 0.86 HSD17B10 (0.44) SLC2A1L3MBTL1MAPTUSP2ALDH1A1
SCHEMBL14991138 0.79 HSD17B10 (0.44) SLC2A1L3MBTL1MAPTHSD17B10
SCHEMBL8300776 0.78 POLB (0.49) L3MBTL1MAPTALDH1A1LMNAPOLB
SCHEMBL668653 0.78 L3MBTL1 (0.64) L3MBTL1MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL2336447 0.78 ERN1 (0.50) L3MBTL1MAPTALDH1A1LMNAHTT
SCHEMBL30965843 0.78 L3MBTL1 (0.64) L3MBTL1MAPTALDH1A1LMNASMN1; SMN2
SCHEMBL1803007 0.77 HSD17B10 (0.42) SLC2A1L3MBTL1MAPTALDH1A1HSD17B10
SCHEMBL1803005 0.77 HSD17B10 (0.42) SLC2A1L3MBTL1MAPTSMN1; SMN2HSD17B10
SCHEMBL10785102 0.76 MPL (0.49) L3MBTL1MAPTALDH1A1LMNAHTT
SCHEMBL18700972 0.76 PRKAB2 (0.48) L3MBTL1MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3860997-B1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF CERTAIN NEMATICIDAL SULFONAMIDES CORTEVA AGRISCIENCE LLC (US) 2023-06-28 EP disclosed