Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.50 |
| ▸ | PRKCI | P41743 | 4/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.50 |
| ▸ | PRKACA | P17612 | 3/20 | 0.50 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.50 |
| ▸ | CIT | O14578 | 2/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.50 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.50 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.50 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.50 |
| ▸ | CDK9 | P50750 | 2/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | PRKCB | P05771 | 1/20 | 0.50 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | MARK3 | P27448 | 1/20 | 0.50 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.50 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3093132 | 0.79 | PRKCI (0.55) | ROCK2ROCK1PRKCIPRKD3PRKACA | |
| SCHEMBL858590 | 0.76 | NUDT1 (0.59) | ROCK2ROCK1PRKCIPRKD3PRKACA | |
| SCHEMBL25754402 | 0.75 | LATS1 (0.53) | ROCK2ROCK1PRKCIPRKD3PRKACA | |
| SCHEMBL857995 | 0.74 | ROCK2 (0.50) | ROCK2ROCK1PRKCIPRKD3PRKACA | |
| SCHEMBL84365 | 0.74 | PRKCI (0.53) | ROCK2ROCK1PRKCIPRKD3PRKACA | |
| SCHEMBL14620679 | 0.72 | ROCK1 (0.51) | ROCK2ROCK1PRKCIPRKD3PRKACA | |
| SCHEMBL24492983 | 0.71 | PRKCI (0.50) | ROCK2ROCK1PRKCIPRKD3PRKACA | |
| SCHEMBL8687438 | 0.71 | CIT (0.59) | ROCK2ROCK1PRKCIPRKD3PRKACA | |
| SCHEMBL8688105 | 0.71 | PRKCI (0.55) | ROCK2ROCK1PRKCIPRKD3PRKACA | |
| SCHEMBL1815838 | 0.71 | HPGDS (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |