Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.53 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.53 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.50 |
| ▸ | PRKCI | P41743 | 4/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 4/20 | 0.45 |
| ▸ | PRKACA | P17612 | 4/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.45 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | PAK4 | O96013 | 2/20 | 0.45 |
| ▸ | LTK | P29376 | 2/20 | 0.45 |
| ▸ | GRK5 | P34947 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | CLK2 | P49760 | 2/20 | 0.45 |
| ▸ | CDK7 | P50613 | 2/20 | 0.45 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3093132 | 0.79 | PRKCI (0.55) | ROCK1PRKCIAXLJAK2PRKACA | |
| SCHEMBL25753363 | 0.75 | ROCK2 (0.50) | ROCK1PRKCIAXLJAK2PRKACA | |
| SCHEMBL857824 | 0.74 | ROCK1 (0.50) | ROCK1PRKCIAXLJAK2PRKACA | |
| SCHEMBL179480 | 0.74 | PRKCI (0.53) | ROCK1PRKCIAXLJAK2PRKACA | |
| SCHEMBL26930260 | 0.72 | LATS1 (0.50) | LATS1LATS2ROCK1PRKCIJAK2 | |
| SCHEMBL29938802 | 0.71 | PRKCI (0.50) | ROCK1PRKCIAXLJAK2PRKACA | |
| SCHEMBL858483 | 0.71 | ROCK1 (0.57) | ROCK1PRKCIAXLJAK2PRKACA | |
| SCHEMBL857993 | 0.71 | TTBK1 (0.59) | ROCK1PRKCIAXLJAK2PRKACA | |
| SCHEMBL20547424 | 0.71 | LATS1 (1.00) | LATS1LATS2PRKCIDYRK1BIGF1R | |
| SCHEMBL91443 | 0.71 | PRKCI (0.59) | ROCK1PRKCIAXLJAK2PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203087-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | RNGTT, NSUN2, ALKBH1 | LATS1 4479/4885LATS2 4532/4885ROCK1 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.