Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | DCAF1 | Q9Y4B6 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24036979 | 1.00 | WDR5 (0.43) | WDR5PNPGLAADRB2ADRB1 | |
| SCHEMBL17857554 | 0.90 | L3MBTL1 (0.40) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL18898546 | 0.90 | L3MBTL1 (0.40) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17841455 | 0.88 | CTSA (0.44) | DCAF1MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL17841456 | 0.88 | CTSA (0.44) | DCAF1MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL18898567 | 0.88 | EPHX2 (0.37) | WDR5ADRB1ADRB3DCAF1ALDH1A1 | |
| SCHEMBL25753602 | 0.88 | L3MBTL1 (0.37) | WDR5MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL25622879 | 0.88 | L3MBTL1 (0.37) | WDR5MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL24036777 | 0.88 | L3MBTL1 (0.37) | WDR5MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL24036985 | 0.86 | KCNA5 (0.47) | MEN1KMT2AALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | UBE CORPORATION (JP) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | DHFR, DPYD, CYP2D6 | WDR5 2145/4885PNP 189/4885GLA 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.