Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753806 | 0.89 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL25751670 | 0.71 | SIGMAR1 (0.48) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9668729 | 0.69 | SIGMAR1 (0.64) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8026728 | 0.67 | MEN1 (0.64) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9607913 | 0.67 | SIGMAR1 (0.48) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL25751667 | 0.66 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3257577 | 0.66 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL10133974 | 0.66 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2452595 | 0.66 | SIGMAR1 (0.58) | SIGMAR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL610584 | 0.66 | NPC1 (1.00) | SIGMAR1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |