Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753821 | 0.89 | SIGMAR1 (0.48) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL25751667 | 0.75 | SIGMAR1 (0.42) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL9607913 | 0.73 | SIGMAR1 (0.48) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL2234870 | 0.69 | MEN1 (0.72) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL11228832 | 0.68 | SIGMAR1 (0.69) | SIGMAR1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL11391103 | 0.68 | CYP2D6 (0.41) | SIGMAR1DRD3CYP2D6MC4RALDH1A1 | |
| SCHEMBL25766991 | 0.68 | INMT (0.33) | — | |
| SCHEMBL11504050 | 0.67 | S1PR3 (0.41) | MEN1NPC1RAB9AKMT2AS1PR1 | |
| SCHEMBL11504049 | 0.67 | S1PR3 (0.41) | MEN1NPC1RAB9AKMT2AS1PR1 | |
| SCHEMBL23806561 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203484-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-06-29 | — | — | US | disclosed |