Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | CDC25A | P30304 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25753957 | 0.95 | KDM4E (0.46) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL25753851 | 0.87 | RECQL (0.49) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL30005823 | 0.84 | MAPT (0.56) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL4446630 | 0.84 | MAPT (0.56) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL25753887 | 0.84 | HDAC2 (0.49) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL21939833 | 0.84 | PTPRC (0.49) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL4451690 | 0.83 | HDAC2 (0.48) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL21940137 | 0.83 | HDAC2 (0.51) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL11421782 | 0.80 | MAPT (0.55) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL25753950 | 0.80 | PTPRC (0.47) | LMNAMAPTKDM4EALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615502-B1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIV TASMANIA (AU) | 2023-06-21 | — | — | EP | disclosed |