Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PTPRC | P08575 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21939833 | 0.89 | PTPRC (0.49) | RECQLPTPRCALDH1A1KDM4ELMNA | |
| SCHEMBL25753852 | 0.87 | LMNA (0.48) | PTPRCALDH1A1KDM4ELMNAPTPN13 | |
| SCHEMBL25753950 | 0.85 | PTPRC (0.47) | RECQLPTPRCALDH1A1KDM4ELMNA | |
| SCHEMBL25753957 | 0.82 | KDM4E (0.46) | PTPRCALDH1A1KDM4ELMNAPTPN13 | |
| SCHEMBL25753887 | 0.82 | HDAC2 (0.49) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL13649352 | 0.81 | MAPT (0.51) | PTPRCALDH1A1KDM4ELMNAPTPN13 | |
| SCHEMBL21940137 | 0.81 | HDAC2 (0.51) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL4451690 | 0.81 | HDAC2 (0.48) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL25753979 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL21878898 | 0.77 | TRPV1 (0.50) | ALDH1A1KDM4ELMNAHDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615502-B1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIV TASMANIA (AU) | 2023-06-21 | — | — | EP | disclosed |