Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 4/20 | 0.43 |
| ▸ | CDC25B | P30305 | 3/20 | 0.43 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.43 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21878874 | 0.84 | CDC25A (0.54) | CDC25ACDC25BMAP2K7S100A4CYP19A1 | |
| SCHEMBL30692083 | 0.84 | CDC25A (0.54) | CDC25ACDC25BMAP2K7S100A4CYP19A1 | |
| SCHEMBL25754015 | 0.84 | ALDH1A1 (0.44) | CDC25AS100A4HPGDMALT1CYP19A1 | |
| SCHEMBL25754017 | 0.83 | PTPRC (0.48) | CDC25ACDC25BPTPRCPTPN13HPGD | |
| SCHEMBL21939613 | 0.79 | TRPV1 (0.50) | MALT1LMNAPKMHDAC6 | |
| SCHEMBL28109252 | 0.79 | MAPT (0.51) | CDC25ACDC25BMAP2K7S100A4CYP19A1 | |
| SCHEMBL6535771 | 0.78 | CDC25A (0.56) | CDC25ACDC25BMAP2K7S100A4KEAP1 | |
| SCHEMBL21939610 | 0.77 | FAAH (0.48) | — | |
| SCHEMBL25753852 | 0.76 | LMNA (0.48) | CDC25ACDC25BMAP2K7S100A4PTPRC | |
| SCHEMBL21939957 | 0.76 | PARP1 (0.47) | HPGDPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615502-B1 | THERAPEUTIC COMPOUNDS AND METHODS | UNIV TASMANIA (AU) | 2023-06-21 | — | — | EP | disclosed |