Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25625378 | 0.84 | CTSA (0.40) | ALDH1A1SMN1; SMN2MAPTMEN1HPGD | |
| SCHEMBL24036571 | 0.83 | MEN1 (0.38) | ALDH1A1POLBMAPTMEN1HPGD | |
| SCHEMBL25625468 | 0.81 | LMNA (0.37) | SMN1; SMN2POLBMEN1HPGDKMT2A | |
| SCHEMBL24036584 | 0.81 | CTSA (0.42) | ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25753758 | 0.80 | ALDH1A1 (0.36) | ALDH1A1SMN1; SMN2POLBAPPMAPT | |
| SCHEMBL24036949 | 0.80 | RIPK1 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2ABACE1 | |
| SCHEMBL18404162 | 0.72 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2POLBMAPTMEN1 | |
| SCHEMBL25625198 | 0.72 | AKT1 (0.40) | ALDH1A1POLBMAPTMEN1KMT2A | |
| SCHEMBL6670889 | 0.71 | SLC1A3 (0.43) | POLBMAPTMEN1KMT2A | |
| SCHEMBL25625467 | 0.71 | POLB (0.39) | ALDH1A1SMN1; SMN2POLBMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | UBE CORPORATION (JP) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192661-A1 | 1, 4, 5, 6-TETRAHYDROPYRIMIDINE-2-AMINE DERIVATIVE | DHFR, DPYD, CYP2D6 | ALDH1A1 208/4885SMN1; SMN2 1305/4885POLB 860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.