SCHEMBL25754397

SCHEMBL25754397

CC#CCOCC(N)CN1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.34
ERAP2 Q6P179 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.31
LMNA P02545 1/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25754421 0.92 KMT2A (0.33) ANPEPERAP2MEN1KMT2A
SCHEMBL25754418 0.84 ANPEP (0.33) ANPEPERAP2MEN1KMT2A
SCHEMBL25754425 0.83 PSMB1 (0.33) LMNAKDM4E
SCHEMBL25754420 0.82 ANPEP (0.31) ANPEPERAP2MEN1KMT2A
SCHEMBL25754439 0.82 KMT2A (0.33) ANPEPERAP2MEN1KMT2A
SCHEMBL25754524 0.79 KMT2A (0.38) ANPEPERAP2MEN1KMT2AATM
SCHEMBL25754506 0.77 KMT2A (0.38) ANPEPERAP2MEN1KMT2AATM
SCHEMBL25754411 0.75 HRH3 (0.33) LMNAKDM4E
SCHEMBL25754467 0.75 ABCB1 (0.36) ANPEPERAP2MEN1KMT2APOLB
SCHEMBL28301902 0.70 MEN1 (0.46) ANPEPERAP2MEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 ANPEP 273/4885ERAP2 447/4885MEN1 940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.