SCHEMBL25754418

SCHEMBL25754418

CC#CCCOCC(N)CN1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.33
ERAP2 Q6P179 1/20 0.33
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25754439 0.97 KMT2A (0.33) ANPEPERAP2ALDH1A1KMT2AMEN1
SCHEMBL25754420 0.91 ANPEP (0.31) ANPEPERAP2ALDH1A1KMT2AMEN1
SCHEMBL25754431 0.87 MAPT (0.34)
SCHEMBL25754421 0.87 KMT2A (0.33) ANPEPERAP2ALDH1A1KMT2AMEN1
SCHEMBL25754397 0.84 ANPEP (0.34) ANPEPERAP2KMT2AMEN1
SCHEMBL25754512 0.78 KMT2A (0.36) ANPEPERAP2ALDH1A1KMT2AMEN1
SCHEMBL25754526 0.78 KMT2A (0.37) ANPEPERAP2ALDH1A1KMT2AMEN1
SCHEMBL25754469 0.76 ABCB1 (0.35) ANPEPERAP2ALDH1A1KMT2AMEN1
SCHEMBL25754411 0.76 HRH3 (0.33) ALDH1A1
SCHEMBL25754425 0.75 PSMB1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 ANPEP 273/4885ERAP2 447/4885ALDH1A1 2539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.