Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 6/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL281571 | 0.90 | MCOLN3 (0.65) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL29452168 | 0.89 | ALDH1A1 (0.61) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL25359140 | 0.87 | HTT (0.63) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL23326940 | 0.82 | L3MBTL1 (0.97) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL29451251 | 0.82 | L3MBTL1 (0.97) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL23326896 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL30892438 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL22734825 | 0.81 | L3MBTL1 (1.00) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL6660363 | 0.81 | ALDH1A1 (0.57) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL29451864 | 0.80 | ALDH1A1 (0.69) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | TRAP1, PINK1, TP53BP1 | ALDH1A1 2569/4885KMT2A 4864/4885SMN1; SMN2 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.