Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | GRK6 | P43250 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23846993 | 0.82 | PIN1 (0.66) | PIN1ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL3057838 | 0.78 | PIN1 (1.00) | PIN1NPY5RSCN2A | |
| SCHEMBL23846978 | 0.78 | PIN1 (0.69) | PIN1NPY5RPARP1EGLN1SCN2A | |
| SCHEMBL23736190 | 0.78 | NPY5R (0.58) | PIN1ALDH1A1KDM4ENPY5RAURKA | |
| SCHEMBL14286642 | 0.78 | CCR1 (0.51) | PIN1KDM4EDGAT2SMN1; SMN2 | |
| SCHEMBL28939219 | 0.77 | ALPL (0.59) | PIN1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11632465 | 0.76 | KDM4E (0.71) | PIN1ALDH1A1KDM4ENPY5RPARP1 | |
| SCHEMBL23846991 | 0.76 | NPY5R (0.53) | PIN1ALDH1A1KDM4ENPY5RPARP1 | |
| SCHEMBL15331846 | 0.76 | NPY5R (0.53) | PIN1ALDH1A1KDM4ENPY5RPARP1 | |
| SCHEMBL21686768 | 0.75 | KDM4E (0.53) | PIN1ALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | AMATHUS THERAPEUTICS, INC. (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174523-A1 | BENZENESULFONAMIDE DERIVATIVES AS TRAP1 MODULATORS AND USES THEREOF | TRAP1, PINK1, TP53BP1 | PIN1 3482/4885ALDH1A1 2569/4885KDM4E 4448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.