Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27496380 | 0.79 | CYP2A6 (0.50) | GAAALDH1A1MAPTCYP3A4CYP2C9 | |
| SCHEMBL1127502 | 0.70 | ATM (0.48) | ATMTSHRKDM4EGAANOTUM | |
| SCHEMBL8503384 | 0.70 | CYP2C9 (0.54) | TSHRALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL5378514 | 0.69 | RAB9A (0.40) | EGFRSRCTSHRCYP1A2CYP3A4 | |
| SCHEMBL5369278 | 0.67 | FGFR1 (0.42) | EGFRSRCTSHRCYP2C9CYP2C19 | |
| SCHEMBL761009 | 0.67 | — | — | |
| SCHEMBL12040840 | 0.67 | ATM (0.45) | ATMKDM4EGAANOTUMALDH1A1 | |
| SCHEMBL27657660 | 0.65 | BRD4 (0.50) | KDM4ENOTUMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3658913 | 0.65 | ATM (0.48) | ATMTSHRKDM4EGAANOTUM | |
| SCHEMBL8130354 | 0.65 | ATM (0.48) | ATMTSHRKDM4EGAANOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023121184-A1 | SUBSTITUTED THIAZOLIDINEDIONE DERIVATIVE COMPOUND, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER, COMPRISING SAME | (주)메디픽 | 2023-06-29 | — | — | WO | disclosed |