Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL27390152 | 0.88 | ATM (0.53) | ATMNOTUMCOMTALDH1A1CYP1A2 | |
| SCHEMBL18885212 | 0.83 | RECQL (0.46) | NOTUMALDH1A1CYP1A2KDM4EHPGD | |
| SCHEMBL12270200 | 0.82 | KDM4E (0.32) | ATMCOMTALDH1A1CYP1A2KDM4E | |
| SCHEMBL28064969 | 0.81 | PTGS2 (0.47) | NOTUMALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9799509 | 0.79 | ATM (0.31) | ATMALDH1A1 | |
| SCHEMBL5272522 | 0.79 | BIRC5 (0.46) | ATMNOTUMALDH1A1CYP1A2KDM4E | |
| SCHEMBL7802726 | 0.79 | FAAH (0.34) | ATMALDH1A1HPGDKMT2ALMNA | |
| SCHEMBL8137135 | 0.76 | KEAP1 (0.49) | NOTUMALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL12349882 | 0.76 | CYP2A6 (0.59) | ALDH1A1HSD17B10MAPTCYP3A4GAA | |
| SCHEMBL2615405 | 0.76 | TDP1 (0.40) | ALDH1A1CYP1A2CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920299-B1 | COMPOSITIONS CONTAINING PYRROLO-OXAZOLES FOR DYEING KERATIN FIBRES; THEIR USE FOR DYEING AS COUPLERS, METHOD OF DYEING | OREAL (FR) | 2002-03-20 | — | — | EP | claimed |
| EP-0920299-A2 | COMPOSITIONS CONTAINING PYRROLO-OXAZOLES FOR DYEING KERATIN FIBRES; THEIR USE FOR DYEING AS COUPLERS, METHOD OF DYEING | L'OREAL (FR) | 1999-06-09 | — | — | EP | claimed |
| WO-1998008487-A2 | COMPOSITIONS CONTAINING PYRROLO-OXAZOLES FOR DYEING KERATIN FIBRES; THEIR USE FOR DYEING AS COUPLERS, METHOD OF DYEING | L'OREAL (FR) | 1998-03-05 | — | — | WO | claimed |
| CN-119570045-A | Copper-iron bimetallic MOFs material, preparation method and application thereof, and method for preparing N-substituted pyrrole compound | 中国石油化工股份有限公司 | 2025-03-07 | — | — | CN | disclosed |
| WO-2023192901-A9 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |
| WO-2023192901-A1 | QUINOLINE DERIVATIVES AS MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-10-05 | — | — | WO | disclosed |
| US-20230183256-A1 | PROTEASOME ACTIVITY ENHANCING COMPOUNDS | YUMANITY THERAPEUTICS, INC. | 2023-06-15 | — | — | US | disclosed |
| US-20230183256-A1 | PROTEASOME ACTIVITY ENHANCING COMPOUNDS | YUMANITY THERAPEUTICS, INC. | 2023-06-15 | — | — | US | disclosed |
| US-20230172057-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE | WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| US-11560385-B2 | Proteasome activity enhancing compounds | PROTEOSTASIS THERAPEUTICS, INC. (US) | 2023-01-24 | — | — | US | disclosed |
| WO-2022132048-A1 | PHOSPHORUS COMPOUNDS AND METHODS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-06-23 | — | — | WO | disclosed |
| US-5858571-A | TREATING A PULVERIZED HYDROGEN ABSORBING ALLOY WITH A SOLUTION COMPRISING A CONJUGATED UNSATURATED COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| EP-0872903-A1 | Method for making hydrogen storage alloy powder and electrode comprising the alloy powder | Shin-Etsu Chemical Co., Ltd. (JP) | 1998-10-21 | — | — | EP | disclosed |
| WO-1998025896-A1 | SUBSTITUTED PYRROLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-06-18 | — | — | WO | disclosed |
| WO-1998008487-A2 | COMPOSITIONS CONTAINING PYRROLO-OXAZOLES FOR DYEING KERATIN FIBRES; THEIR USE FOR DYEING AS COUPLERS, METHOD OF DYEING | L'OREAL (FR) | 1998-03-05 | — | — | WO | disclosed |
| EP-0172427-B1 | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-RE32896-E | GROUP 1B OR 4B METAL OXIDES AS CATALYSTS | ETHYL CORPORATION (US) | 1989-03-28 | — | — | US | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| US-4626592-A | WITH A CYCLIC ETHER AND B-SUBGROUP METAL OXIDE ALKYLATION CATALYST | ETHYL CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560385-B2 | Proteasome activity enhancing compounds | PSMG3, PSME3, PSMC4 | ATM 2649/4885NOTUM 2862/4885COMT 3960/4885 |
| US-20230172057-A1 | HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE | CHRM1, CHRM2, CHRM4 | ATM 2383/4885NOTUM 3751/4885COMT 3365/4885 |
| US-20230183256-A1 | PROTEASOME ACTIVITY ENHANCING COMPOUNDS | PSMG3, PSME3, PSMC4 | ATM 2649/4885NOTUM 2862/4885COMT 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.