SCHEMBL25755812

SCHEMBL25755812

[N-]=[N+]=NCCCCOCCCCN

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.33
CYP1A2 P05177 1/20 0.33
ALOX15 P16050 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
DHPS P49366 1/20 0.32
DDAH1 O94760 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25756204 0.96 ODC1 (0.33)
SCHEMBL25756344 0.94 ODC1 (0.32) DHPS
SCHEMBL27160292 0.89 MGMT (0.33)
SCHEMBL23226055 0.89 MGMT (0.36)
SCHEMBL25755568 0.89 ODC1 (0.35)
SCHEMBL16852231 0.89 MGMT (0.31)
SCHEMBL17334555 0.88 DNM1 (0.30)
SCHEMBL13658545 0.87 ODC1 (0.33)
SCHEMBL21357412 0.86 IDUA (0.33)
SCHEMBL13986345 0.86

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 NFKB1 2897/4885CYP1A2 3367/4885ALOX15 3842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.