SCHEMBL25756344

SCHEMBL25756344

[N-]=[N+]=NCCCCCOCCCN

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 1/20 0.32
DHPS P49366 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25756204 0.98 ODC1 (0.33) ODC1
SCHEMBL25755812 0.94 NFKB1 (0.33) DHPS
SCHEMBL25755568 0.91 ODC1 (0.35) ODC1
SCHEMBL13658545 0.89 ODC1 (0.33) ODC1
SCHEMBL21357412 0.89 IDUA (0.33)
SCHEMBL27160292 0.88 MGMT (0.33)
SCHEMBL23571410 0.87 ODC1 (0.35) ODC1
SCHEMBL16852231 0.87 MGMT (0.31)
SCHEMBL17334555 0.86 DNM1 (0.30)
SCHEMBL22895263 0.85 MGMT (0.36) ODC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM EUBULUS BIOTHERAPEUTICS (HONG KONG) LIMITED (HK) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210999-A1 TARGETED PROTEASE DEGRADATION (TED) PLATFORM UCHL3, UBE2L3, ADAM33 ODC1 4097/4885DHPS 4611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.