Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL678612 | 0.82 | NR1H2 (0.59) | NR1H2NR1H3 | |
| SCHEMBL5772639 | 0.78 | NR1H2 (0.42) | NR1H2NR1H3 | |
| SCHEMBL20972931 | 0.76 | NR1H2 (0.43) | NR1H2NR1H3 | |
| SCHEMBL8083285 | 0.75 | — | — | |
| SCHEMBL2579803 | 0.75 | NR1H2 (0.53) | NR1H2NR1H3 | |
| SCHEMBL22041208 | 0.74 | NR1H2 (0.48) | NR1H2NR1H3 | |
| SCHEMBL3378809 | 0.73 | NR1H2 (0.52) | NR1H2NR1H3CYP2A6 | |
| SCHEMBL3381733 | 0.73 | CA1 (0.48) | NR1H2NR1H3CYP1A2CYP2A6 | |
| SCHEMBL10324259 | 0.71 | NR1H2 (0.50) | NR1H2NR1H3 | |
| SCHEMBL3378627 | 0.71 | NR1H2 (0.50) | NR1H2NR1H3CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048977-B2 | Organosilicon polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-01 | — | — | US | claimed |
| US-20090069525-A1 | ORGANOSILICON POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-03-12 | — | — | US | claimed |
| WO-2007130014-A1 | ORGANOSILICON POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-15 | — | — | WO | claimed |
| US-8048977-B2 | Organosilicon polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-01 | — | — | US | disclosed |
| US-20090069525-A1 | ORGANOSILICON POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-03-12 | — | — | US | disclosed |
| WO-2007130014-A1 | ORGANOSILICON POLYMERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-15 | — | — | WO | disclosed |