Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199662 | 0.85 | ALDH1A1 (0.35) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL25756945 | 0.82 | DHFR (0.38) | FYNDHFRKDM4EALDH1A1LMNA | |
| SCHEMBL25756944 | 0.80 | PCSK9 (0.35) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL27199377 | 0.76 | MAPT (0.35) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL27199703 | 0.71 | IRAK4 (0.35) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL30895044 | 0.70 | PCSK9 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL27199546 | 0.70 | NPBWR1 (0.33) | FYNDHFRKDM4EALDH1A1LMNA | |
| SCHEMBL27199460 | 0.68 | ALDH1A1 (0.34) | KDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL24565970 | 0.66 | TLR7 (0.33) | — | |
| SCHEMBL27199421 | 0.66 | GAA (0.35) | KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023109954-A1 | TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF | LYNK PHARMACEUTICALS CO. LTD. (CN) | 2023-06-22 | — | — | WO | disclosed |