Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.60 |
| ▸ | SRC | P12931 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR1F | P30939 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218524 | 0.82 | GABRA1 (0.52) | EGFRALDH1A1HTR6KDM4EHTR1A | |
| SCHEMBL7359271 | 0.81 | HTR6 (0.51) | ALDH1A1HTR6KDM4EHTR1ADRD2 | |
| SCHEMBL3280964 | 0.81 | EGFR (0.57) | EGFRSRCALDH1A1HTR6KDM4E | |
| SCHEMBL27905352 | 0.81 | EGFR (0.58) | EGFRSRCALDH1A1KDM4EGABRP | |
| SCHEMBL9223733 | 0.81 | GABRA1 (0.51) | EGFRALDH1A1HTR6KDM4EHTR1A | |
| SCHEMBL5268569 | 0.78 | HTR6 (0.70) | EGFRSRCALDH1A1HTR6KDM4E | |
| SCHEMBL7127236 | 0.78 | EGFR (0.71) | EGFRSRCALDH1A1HTR6KDM4E | |
| SCHEMBL25757058 | 0.78 | EGFR (0.54) | EGFRSRCMAPT | |
| SCHEMBL30688567 | 0.77 | NR4A2 (0.60) | ALDH1A1KDM4EGABRPGABRDGABRA1 | |
| SCHEMBL27478799 | 0.77 | EGFR (0.69) | EGFRSRCALDH1A1HTR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091945-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000481-A1 | CYCLIC CARBAMATES AND ISOXAZOLIDINES AS IIB/IIIA ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-01-06 | — | — | WO | disclosed |