SCHEMBL25757573

SCHEMBL25757573

CCCCCCCCC(CCCCCC)C(=O)OCCCCC1CNCC(CCCCOC(=O)C(CCCCCC)CCCCCCCC)C1

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 3/20 0.38
GBA1 P04062 1/20 0.36
EPHX1 P07099 1/20 0.36
CA2 P00918 1/20 0.36
DRD3 P35462 1/20 0.35
SLC6A3 Q01959 1/20 0.35
ACHE P22303 5/20 0.35
TSHR P16473 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31645488 0.84 S1PR3 (0.39) NAAAGBA1EPHX1CA2ACHE
SCHEMBL31645615 0.84 S1PR3 (0.39) NAAAGBA1EPHX1CA2ACHE
SCHEMBL31645650 0.84 S1PR3 (0.39) NAAAGBA1EPHX1CA2ACHE
SCHEMBL31645257 0.84 S1PR3 (0.39) NAAAGBA1EPHX1CA2ACHE
SCHEMBL31409863 0.81 GBA1 (0.54) NAAAGBA1EPHX1CA2ACHE
SCHEMBL296648 0.80 NAAA (0.55) NAAAEPHX1CA2ACHETSHR
SCHEMBL5179238 0.80 NAAA (0.55) NAAAEPHX1CA2ACHETSHR
SCHEMBL730516 0.80 NAAA (0.55) NAAAEPHX1CA2ACHETSHR
SCHEMBL698630 0.80 NAAA (0.55) NAAAEPHX1CA2ACHETSHR
SCHEMBL20512287 0.80 NAAA (0.55) NAAAEPHX1CA2ACHETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4402123-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF Renagade Therapeutics Management Inc. (US) 2024-07-24 EP disclosed
US-11773061-B2 Cyclic lipids and methods of use thereof RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-10-03 US disclosed
US-11773061-B2 Cyclic lipids and methods of use thereof RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-10-03 US disclosed
US-11773061-B2 Cyclic lipids and methods of use thereof RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-10-03 US disclosed
US-20230202977-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. 2023-06-29 US disclosed
US-20230202977-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. 2023-06-29 US disclosed
US-20230202977-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. 2023-06-29 US disclosed
WO-2023044333-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF RENAGADE THERAPEUTICS MANAGEMENT INC. (US) 2023-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773061-B2 Cyclic lipids and methods of use thereof SGMS1, SGMS2, LNPEP NAAA 1398/4885GBA1 236/4885EPHX1 2960/4885
US-20230202977-A1 CYCLIC LIPIDS AND METHODS OF USE THEREOF SGMS1, SGMS2, LNPEP NAAA 1398/4885GBA1 236/4885EPHX1 2960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.