SCHEMBL730516

SCHEMBL730516

CCCCCCCCCCCCCCC(CCCCCCCC)C(=O)OCCCCCCCCCCCC

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.55
CA2 P00918 2/20 0.52
EPHX1 P07099 1/20 0.52
TSHR P16473 3/20 0.50
ZDHHC7 Q9NXF8 1/20 0.48
MAPT P10636 1/20 0.48
HCAR2 Q8TDS4 1/20 0.47
RAD52 P43351 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
CA1 P00915 1/20 0.47
FAAH O00519 1/20 0.46
ALDH1A1 P00352 1/20 0.46
LMNA P02545 1/20 0.46
GRIK1 P39086 1/20 0.46
GRIK2 Q13002 1/20 0.46
ACHE P22303 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL294411 1.00 NAAA (0.55) NAAACA2EPHX1TSHRZDHHC7
SCHEMBL20535742 1.00 NAAA (0.55) NAAACA2EPHX1TSHRZDHHC7
SCHEMBL296648 1.00 NAAA (0.55) NAAACA2EPHX1TSHRZDHHC7
SCHEMBL5179238 1.00 NAAA (0.55) NAAACA2EPHX1TSHRZDHHC7
SCHEMBL20767416 1.00 NAAA (0.55) NAAACA2EPHX1TSHRZDHHC7
SCHEMBL20512287 1.00 NAAA (0.55) NAAACA2EPHX1TSHRZDHHC7
SCHEMBL296649 1.00 NAAA (0.55) NAAACA2EPHX1TSHRZDHHC7
SCHEMBL698630 1.00 NAAA (0.55) NAAACA2EPHX1TSHRZDHHC7
SCHEMBL21247597 1.00 NAAA (0.55) NAAACA2EPHX1TSHRZDHHC7
SCHEMBL9770100 1.00 NAAA (0.55) NAAACA2EPHX1TSHRZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1364651-B1 Pharmaceutical composition with deswelling properties SEBAPHARMA GMBH & CO KG (DE) 2005-11-02 EP claimed
CN-118255914-A Copolymer having carbosiloxane dendrimer structure, and composition, cosmetic raw material, film-forming agent and cosmetic containing the copolymer 陶氏东丽株式会社 2024-06-28 CN disclosed
WO-2024132314-A1 SILICONE-FREE HAIR OIL HENKEL AG & CO. KGAA (DE) 2024-06-27 WO disclosed
US-11944697-B2 Manufacturing process for 2-phase spray conditioner HENKEL AG & CO. KGAA (US) 2024-04-02 US disclosed
CN-114040746-B Oil-in-water type cleansing cosmetic 陶氏东丽株式会社 2024-02-27 CN disclosed
CN-113710226-B Cosmetic material 陶氏东丽株式会社 2024-02-27 CN disclosed
CN-117529306-A Nicotinamide Adenine Dinucleotide (NAD) compositions, methods of making and methods of using the same 索维达解决方案有限公司 2024-02-06 CN disclosed
CN-115023271-B Hair improvement method 日本精化株式会社 2024-01-30 CN disclosed
CN-117479945-A Large conductance potassium channel modulators, compositions thereof, methods of making and methods of using the same 依那拉治疗股份有限公司 2024-01-30 CN disclosed
CN-112789027-B Oil-in-water type emulsified cosmetic 陶氏东丽株式会社 2023-11-07 CN disclosed
US-20050037042-A1 Cosmetic or dermatological preparations containing licochalcone A or an extract of radix glycyrrhizae inflatae, containing licochalcone A BEIERSDORF AG (DE) 2005-02-17 US disclosed
US-20040235668-A1 Microemulsions as adjuvants for agricultural chemicals COGNIS IP MANAGEMENT GMBH (DE) 2004-11-25 US disclosed
WO-2004080177-A2 MICROEMULSIONS AS ADJUVANTS FOR AGRICULTURAL CHEMICALS COGNIS CORPORATION (US) 2004-09-23 WO disclosed
CN-1473146-A Novel indanylidene compounds ������������� 2004-02-04 CN disclosed
US-20030180278-A1 Use of a combination of active substances containing bioquinones for the production of cosmetic or dermatological preparations GS DEVELOPMENT A.B. (SE) 2003-09-25 US disclosed
US-20030180277-A1 Use of bioquinones for producing cosmetic or dermatological preparations for treating the hair and scalp GS DEVELOPMENT AB (SE) 2003-09-25 US disclosed
US-20020143072-A1 For use in pharmaceutical or cosmetic formulations COLLABORATIVE TECHNOLOGIES, INC. 2002-10-03 US disclosed
US-6086787-A HEATING, THICKENING HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-11 US disclosed
US-5817254-A MIXTURE OF WATER INSOLUBLE OIL, EMULSIFIERS AND WATER HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1998-10-06 US disclosed
US-5494938-A COMPRISINGA WATER INSOLUABLE OIL, ALKYL GLUCOSIDES AND FATTY ACID GLYCERIDES; STORAGE STABILITY, HOMOGENEITY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1996-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030180278-A1 Use of a combination of active substances containing bioquinones for the production of cosmetic or dermatological preparations SDHA, SDHB, SLC25A20 NAAA 1164/4885CA2 1259/4885EPHX1 1898/4885
US-20050037042-A1 Cosmetic or dermatological preparations containing licochalcone A or an extract of radix glycyrrhizae inflatae, containing licochalcone A CUTA, GRHPR, GYPA NAAA 2673/4885CA2 3242/4885EPHX1 1104/4885
US-20030180277-A1 Use of bioquinones for producing cosmetic or dermatological preparations for treating the hair and scalp SDHA, SDHB, SLC25A20 NAAA 973/4885CA2 1650/4885EPHX1 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.