SCHEMBL25757583

SCHEMBL25757583

O=CCn1cc(F)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.49
SMN1; SMN2 Q16637 7/20 0.49
HTT P42858 7/20 0.49
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
LMNA P02545 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
NOD2 Q9HC29 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
IDO1 P14902 1/20 0.38
MAPT P10636 2/20 0.38
HSP90AA1 P07900 1/20 0.38
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15333488 0.78 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2HTTMEN1KMT2A
SCHEMBL15330109 0.78 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2HTTMEN1KMT2A
SCHEMBL8527697 0.78 MEN1 (0.55) ALDH1A1SMN1; SMN2HTTMEN1KMT2A
SCHEMBL8527695 0.78 KMT2A (0.40) ALDH1A1SMN1; SMN2HTTMEN1KMT2A
SCHEMBL19233876 0.73 KDM4E (0.70) ALDH1A1SMN1; SMN2HTTKMT2ALMNA
SCHEMBL9701331 0.73 HTR6 (0.62) ALDH1A1KMT2ALMNA
SCHEMBL19232823 0.73 CREBBP (0.64) ALDH1A1SMN1; SMN2HTTMEN1KMT2A
SCHEMBL19234287 0.71 KMT2A (0.51) ALDH1A1HTTMEN1KMT2ALMNA
SCHEMBL9701531 0.70 CDC25A (0.49) CNR2
SCHEMBL13456337 0.70 CYP1A2 (0.56) ALDH1A1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023098738-A1 COMPOUND CONTAINING OXADIAZOLE STRUCTURE AND PREPARATION METHOD THEREFOR AND USE THEREOF, AND FUNGICIDE 江苏中旗科技股份有限公司 2023-06-08 WO disclosed