SCHEMBL25757655

SCHEMBL25757655

CC[n+]1ccc2c(c(I)cn2C2CC2)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL30498493 0.99
Iodide SCHEMBL30498146 0.77
Iodide SCHEMBL30498370 0.73 IL1B (0.35)
Iodide SCHEMBL30498075 0.71
Iodide SCHEMBL30498337 0.70 P2RX7 (0.33)
SCHEMBL23966903 0.67 ADK (0.33)
SCHEMBL29484474 0.67 ADK (0.33)
SCHEMBL25421997 0.62 KDM4E (0.30)
Iodide SCHEMBL30498301 0.57 HDAC8 (0.33)
Iodide SCHEMBL30498093 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023109954-A1 TYK2 INHIBITORS AND COMPOSITIONS AND METHODS THEREOF LYNK PHARMACEUTICALS CO. LTD. (CN) 2023-06-22 WO disclosed