Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654643 | 0.98 | ALDH1A1 (0.49) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL8653231 | 0.98 | ALDH1A1 (0.49) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL8654462 | 0.98 | ALDH1A1 (0.49) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL8652188 | 0.94 | ALDH1A1 (0.51) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL8655261 | 0.86 | ALDH1A1 (0.65) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL8521929 | 0.85 | ALDH1A1 (0.50) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL7152871 | 0.81 | ALDH1A1 (0.78) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL7148358 | 0.81 | ALDH1A1 (0.58) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL11256668 | 0.80 | ALDH1A1 (0.57) | LMNAALDH1A1HPGDTP53TSHR | |
| SCHEMBL11903331 | 0.79 | ALDH1A1 (0.33) | LMNAALDH1A1HPGDTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920647-A | Novel synthesis process of intermediate side chain alcohol of medicine for treating primary hypertension | 苏州虞美景盛新药开发有限公司 | 2022-08-19 | — | — | CN | disclosed |
| WO-2011130852-A1 | PREPARATION OF INTERMEDIATES FOR THE SYNTHESIS OF DIHYDROPYRIDINE CALCIUM CHANNEL BLOCKERS | ALPHORA RESEARCH INC. (CA) | 2011-10-27 | — | — | WO | disclosed |
| WO-1999001432-A1 | ANTI-DIABETIC AGENT | LATVIAS ORGANISKAS SINTEZES INSTITUTS (LV) | 1999-01-14 | — | — | WO | disclosed |
| US-5843950-A | 1,4-dihydropyridine compound and pharmaceutical composition containing the same | NIKKEN CHEMICALS CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| US-4841054-A | A LOW TOXICITY, HIGH STABILITY MEDICATION FOR HYPERTENSIVE ACTIVITY | INSTITUTE ORGANICHESKOGO SINTEZA AKADEMII NAUK LATVISISKOI SSR | 1989-06-20 | — | — | US | disclosed |