Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256668 | 0.98 | ALDH1A1 (0.57) | ALDH1A1HPGDTSHRHSD17B10LMNA | |
| SCHEMBL7107070 | 0.94 | LMNA (0.69) | ALDH1A1HPGDTSHRHSD17B10LMNA | |
| SCHEMBL9831538 | 0.89 | LMNA (0.71) | ALDH1A1HPGDTSHRHSD17B10LMNA | |
| SCHEMBL11292115 | 0.88 | TSHR (0.74) | ALDH1A1HPGDTSHRHSD17B10LMNA | |
| SCHEMBL7152871 | 0.87 | ALDH1A1 (0.78) | ALDH1A1HPGDTSHRHSD17B10LMNA | |
| SCHEMBL5359112 | 0.82 | GAA (0.59) | ALDH1A1HPGDTSHRHSD17B10LMNA | |
| SCHEMBL1663817 | 0.82 | LMNA (0.87) | ALDH1A1HPGDTSHRHSD17B10LMNA | |
| SCHEMBL8521929 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRHSD17B10LMNA | |
| SCHEMBL2576010 | 0.81 | LMNA (0.50) | ALDH1A1HPGDTSHRHSD17B10LMNA | |
| SCHEMBL17367955 | 0.80 | ALDH1A1 (0.68) | ALDH1A1HPGDTSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030230478-A1 | Process for the preparation of 1,4 - dihydropyridines and novel 1,4-dihydropyridines useful as therapeutic agents | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2003-12-18 | — | — | US | disclosed |
| WO-2003099790-A1 | PROCESS FOR THE PREPARATION OF 1,4-DIHYDROPYRIDINES AND NOVEL 1,4-DIHYDROPYRIDINES USEFUL AS THERAPEUTIC AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2003-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030230478-A1 | Process for the preparation of 1,4 - dihydropyridines and novel 1,4-dihydropyridines useful as therapeutic agents | HRH4, ODC1, OGDH | ALDH1A1 29/4885HPGD 543/4885TSHR 2934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.