Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653231 | 1.00 | ALDH1A1 (0.49) | ALDH1A1LMNATP53HPGDTSHR | |
| SCHEMBL8654462 | 1.00 | ALDH1A1 (0.49) | ALDH1A1LMNATP53HPGDTSHR | |
| SCHEMBL2576010 | 0.98 | LMNA (0.50) | ALDH1A1LMNATP53HPGDTSHR | |
| SCHEMBL8652188 | 0.93 | ALDH1A1 (0.51) | ALDH1A1LMNATP53HPGDTSHR | |
| SCHEMBL8655261 | 0.85 | ALDH1A1 (0.65) | ALDH1A1LMNATP53HPGDTSHR | |
| SCHEMBL8521929 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNATP53HPGDTSHR | |
| SCHEMBL7148358 | 0.79 | ALDH1A1 (0.58) | ALDH1A1LMNATP53HPGDTSHR | |
| SCHEMBL11903331 | 0.78 | ALDH1A1 (0.33) | ALDH1A1LMNATP53HPGDTSHR | |
| SCHEMBL7379538 | 0.77 | SMN1; SMN2 (0.56) | ALDH1A1LMNATP53HPGDTSHR | |
| SCHEMBL7662266 | 0.77 | TDP1 (0.43) | ALDH1A1LMNATP53HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843950-A | 1,4-dihydropyridine compound and pharmaceutical composition containing the same | NIKKEN CHEMICALS CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |