Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8652188 | 0.88 | ALDH1A1 (0.51) | ALDH1A1LMNAHPGDHSD17B10TP53 | |
| SCHEMBL9671967 | 0.88 | ALDH1A1 (0.87) | ALDH1A1LMNAHPGDHSD17B10TP53 | |
| SCHEMBL2576010 | 0.86 | LMNA (0.50) | ALDH1A1LMNAHPGDHSD17B10TP53 | |
| SCHEMBL8654462 | 0.85 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDHSD17B10TP53 | |
| SCHEMBL8654643 | 0.85 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDHSD17B10TP53 | |
| SCHEMBL8653231 | 0.85 | ALDH1A1 (0.49) | ALDH1A1LMNAHPGDHSD17B10TP53 | |
| SCHEMBL9797407 | 0.83 | GAA (0.46) | ALDH1A1LMNAHPGDHSD17B10TP53 | |
| SCHEMBL9139821 | 0.79 | ALDH1A1 (1.00) | ALDH1A1LMNAHPGDHSD17B10TP53 | |
| SCHEMBL11292115 | 0.79 | TSHR (0.74) | ALDH1A1LMNAHPGDHSD17B10TP53 | |
| SCHEMBL28735864 | 0.75 | ADORA3 (0.50) | ALDH1A1LMNAHPGDHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5843950-A | 1,4-dihydropyridine compound and pharmaceutical composition containing the same | NIKKEN CHEMICALS CO., LTD. (JP) | 1998-12-01 | — | — | US | disclosed |
| US-4358529-A | BINDER, A HEXAARYLBIIMIDAZOLE, A DIHYDROPYRIDINE, AND AN IMIDOTHIOESTER OR A TAUTOMER; NONSILVER PHOTOGRAPHY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-11-09 | — | — | US | disclosed |