Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25762019 | 0.89 | CYP19A1 (0.43) | CYP19A1MAPTUGT1A4PDE4DFNTA | |
| SCHEMBL2484409 | 0.86 | ALDH1A1 (0.46) | CYP19A1MAPTS1PR3ARALDH1A1 | |
| SCHEMBL25077137 | 0.81 | P2RX3 (0.42) | CYP19A1S1PR3ALOX5APKDM4ECYP1A2 | |
| SCHEMBL25077473 | 0.78 | CYP19A1 (0.36) | CYP19A1S1PR3ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL2076101 | 0.78 | S1PR3 (0.41) | CYP19A1S1PR3ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL25077413 | 0.74 | CYP19A1 (0.42) | CYP19A1S1PR3 | |
| SCHEMBL25077412 | 0.74 | CYP19A1 (0.47) | CYP19A1S1PR3 | |
| SCHEMBL1823760 | 0.73 | CYP19A1 (0.42) | CYP19A1MAPTALDH1A1KDM4ECYP2C19 | |
| SCHEMBL15828736 | 0.72 | KMT2A (0.47) | MAPTALDH1A1KDM4E | |
| SCHEMBL25077354 | 0.72 | CYP1A2 (0.64) | MAPTS1PR3ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212199-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212199-A1 | PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | PHOSPHO1, SGMS1, SGMS2 | CYP19A1 2757/4885MAPT 3933/4885UGT1A4 2790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.