Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 13/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25764092 | 0.83 | CYP11B2 (0.47) | GRIN2B | |
| SCHEMBL25771002 | 0.79 | MAP4K4 (0.43) | GRIN2BGRIN1HRH1 | |
| SCHEMBL25764706 | 0.78 | PDGFRB (0.51) | GRIN2BGRIN1AKR1C3AKR1C2 | |
| SCHEMBL2609337 | 0.77 | ALDH1A1 (0.56) | ALDH1A1GAAATMGRIN2BL3MBTL1 | |
| SCHEMBL12303237 | 0.76 | KMT2A (0.44) | ALDH1A1GAAL3MBTL1 | |
| SCHEMBL25764095 | 0.76 | GABRG2 (0.51) | — | |
| SCHEMBL25763766 | 0.75 | CYP11B2 (0.52) | ALDH1A1GAAATMGRIN2BGRIN1 | |
| SCHEMBL14832192 | 0.74 | ALDH1A1 (0.59) | ALDH1A1GAAATMGRIN2BL3MBTL1 | |
| SCHEMBL18854065 | 0.74 | ALDH1A1 (0.46) | ALDH1A1GAAATML3MBTL1SCN2A | |
| SCHEMBL25763796 | 0.73 | PDGFRB (0.43) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |