Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 2/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25764075 | 0.87 | AR (0.49) | CYP11B2NR1H3NR1H2ALDH1A1GAA | |
| SCHEMBL25764079 | 0.86 | ESR1 (0.39) | CYP11B2NR1H3NR1H2 | |
| SCHEMBL25764072 | 0.86 | MAP4K4 (0.40) | CYP11B2NR1H3NR1H2ALDH1A1GAA | |
| SCHEMBL25763768 | 0.85 | PGR (0.53) | CYP11B2PDGFRBPDGFRANR1H3NR1H2 | |
| SCHEMBL25763772 | 0.83 | FYN (0.43) | CYP11B2NR1H3NR1H2ALDH1A1GAA | |
| SCHEMBL25763769 | 0.83 | KCNH2 (0.48) | NR1H3NR1H2GRIN2BGRIN1 | |
| SCHEMBL25764092 | 0.81 | CYP11B2 (0.47) | CYP11B2PDGFRBPDGFRAGRIN2BIDO1 | |
| SCHEMBL25763803 | 0.80 | PIK3CD (0.37) | CYP11B2NR1H3NR1H2GRIN2B | |
| SCHEMBL21419075 | 0.77 | TRPA1 (0.33) | CYP11B2NR1H3NR1H2 | |
| SCHEMBL25764094 | 0.75 | ALDH1A1 (0.53) | ALDH1A1GAAATMGRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116835-A1 | MULTI-PROTEIN DEGRADATION AGENT HAVING IMIDE SKELETON | 苏州开拓药业股份有限公司 | 2023-06-29 | — | — | WO | disclosed |