Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12260833 | 0.86 | PKM (0.53) | PKMKMT2AMEN1LMNAKLK7 | |
| SCHEMBL257821 | 0.84 | PKM (0.51) | PKMKMT2AMEN1LMNAKLK7 | |
| SCHEMBL18134893 | 0.81 | PKM (0.67) | PKMKMT2AMEN1SMN1; SMN2L3MBTL1 | |
| SCHEMBL10692649 | 0.81 | PKM (0.76) | PKMKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL27776746 | 0.78 | PPARG (0.50) | PKMKMT2AMEN1LMNAHTT | |
| SCHEMBL10053820 | 0.78 | RECQL (0.62) | PKMKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL8935861 | 0.78 | KDM4E (0.52) | PKMKMT2AMEN1CYP2C19L3MBTL1 | |
| SCHEMBL8935862 | 0.78 | KDM4E (0.52) | PKMKMT2AMEN1CYP2C19L3MBTL1 | |
| SCHEMBL4158522 | 0.77 | PKM (0.62) | PKMKMT2AMEN1LMNAHTT | |
| SCHEMBL4162007 | 0.77 | PKM (0.62) | PKMKMT2AMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| EP-2399584-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |