Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18134893 | 0.95 | PKM (0.67) | PKMKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4162007 | 0.92 | PKM (0.62) | PKMKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL4158522 | 0.92 | PKM (0.62) | PKMKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL4158526 | 0.92 | PKM (0.62) | PKMKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL10689090 | 0.88 | ALDH1A1 (0.69) | PKMKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL9502645 | 0.88 | PKM (0.59) | PKMKMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL10693524 | 0.87 | KMT2A (0.70) | PKMKMT2AALDH1A1TSHRKLK7 | |
| SCHEMBL10693790 | 0.81 | KMT2A (0.60) | PKMKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL257848 | 0.81 | PKM (0.71) | PKMKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10694568 | 0.80 | ALDH1A1 (0.57) | PKMKMT2AMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |