Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.52 |
| ▸ | ADH1C | P00326 | 1/20 | 0.52 |
| ▸ | ADH1A | P07327 | 1/20 | 0.52 |
| ▸ | ADH7 | P40394 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2572416 | 1.00 | ADH1B (0.52) | ADH1BADH1CADH1AADH7FBP1 | |
| SCHEMBL2572414 | 1.00 | ADH1B (0.52) | ADH1BADH1CADH1AADH7FBP1 | |
| SCHEMBL28156497 | 0.82 | ALDH1A1 (0.46) | FBP1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL28155608 | 0.82 | FBP1 (0.49) | FBP1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL28155534 | 0.82 | FBP1 (0.49) | FBP1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL28845929 | 0.80 | SIGMAR1 (0.47) | MAPTKMT2AALDH1A1MEN1POLB | |
| SCHEMBL2578810 | 0.78 | FBP1 (0.53) | FBP1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL2578813 | 0.78 | FBP1 (0.53) | FBP1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL2580094 | 0.78 | FBP1 (0.53) | FBP1MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL8713797 | 0.77 | ADH1B (0.65) | ADH1BADH1CADH1AADH7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385034-B1 | Process for the preparation of 1-nitro-4-oxobutanylamides | SYNKOLA S R O (SK) | 2015-12-02 | — | — | EP | disclosed |
| EP-2385034-A2 | Process for the preparation of 1-nitro-4-oxobutanylamides | Synkola, s.r.o. (SK) | 2011-11-09 | — | — | EP | disclosed |