SCHEMBL25789356

SCHEMBL25789356

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4cccc(-c5cnc6ccccn56)c4)c3)n2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.56
KDR P35968 6/20 0.54
FLT3 P36888 5/20 0.52
IRAK4 Q9NWZ3 1/20 0.48
PIK3CA P42336 1/20 0.47
GABRG2 P18507 1/20 0.46
GABRB3 P28472 1/20 0.46
GABRA3 P34903 1/20 0.46
KIT P10721 1/20 0.46
DYRK1A Q13627 2/20 0.45
CHEK1 O14757 1/20 0.45
MAP4K4 O95819 1/20 0.45
CSF1R P07333 1/20 0.45
PRKACA P17612 1/20 0.45
CDK8 P49336 1/20 0.45
MAP2K1 Q02750 1/20 0.45
ACVR1 Q04771 1/20 0.45
MAP4K2 Q12851 1/20 0.45
ROCK1 Q13464 1/20 0.45
AURKB Q96GD4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25789350 0.99 MIF (0.57) MIFKDRFLT3IRAK4PIK3CA
SCHEMBL25789349 0.88 FLT3 (0.67) MIFKDRFLT3IRAK4PIK3CA
SCHEMBL25789355 0.87 FLT3 (0.65) MIFKDRFLT3IRAK4PIK3CA
SCHEMBL25790174 0.81 FLT3 (0.50) MIFKDRFLT3IRAK4PIK3CA
SCHEMBL2650330 0.81 FLT3 (0.74) MIFKDRFLT3IRAK4PIK3CA
SCHEMBL25789360 0.80 FLT3 (0.49) MIFKDRFLT3IRAK4PIK3CA
SCHEMBL30655418 0.78 FLT3 (0.69) MIFKDRFLT3IRAK4PIK3CA
SCHEMBL14138786 0.78 MIF (0.60) MIFKDRFLT3IRAK4PIK3CA
SCHEMBL73247 0.78 BACE1 (0.62) MIFKDRFLT3IRAK4PIK3CA
SCHEMBL73445 0.78 MIF (0.60) MIFKDRFLT3IRAK4PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217820-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-07-06 US disclosed
US-20230217820-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230217820-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TELO2, SOD1, TERT MIF 101/4885KDR 2286/4885FLT3 1889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.