Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825587 | 0.80 | LMNA (0.40) | HSD11B1LMNAPDK1PDK2 | |
| SCHEMBL3825081 | 0.78 | LMNA (0.38) | HSD11B1LMNAPDK1PDK2 | |
| Hydrochloric Acid SCHEMBL3825409 | 0.78 | LMNA (0.39) | HSD11B1LMNAPDK1PDK2TSHR | |
| SCHEMBL25779726 | 0.68 | HSD11B1 (0.36) | HSD11B1LMNAPDK1PDK2 | |
| SCHEMBL15933175 | 0.68 | HSD11B1 (0.36) | HSD11B1PDK1PDK2 | |
| SCHEMBL25790841 | 0.66 | HSD11B1 (0.38) | HSD11B1PDK1PDK2 | |
| SCHEMBL14700224 | 0.63 | PDK1 (0.38) | HSD11B1PDK1PDK2 | |
| SCHEMBL1015670 | 0.63 | HSD11B1 (0.50) | HSD11B1 | |
| SCHEMBL3825584 | 0.62 | HSD11B1 (0.49) | HSD11B1 | |
| SCHEMBL3821041 | 0.62 | CSNK1D (0.46) | HSD11B1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125928-A1 | MENIN INHIBITOR AND USE THEREOF | 成都先导药物开发股份有限公司 | 2023-07-06 | — | — | WO | disclosed |