Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25778214 | 0.77 | CYP1A2 (0.38) | PDE10A | |
| SCHEMBL25778213 | 0.76 | CTSK (0.34) | PKM | |
| SCHEMBL25779726 | 0.73 | HSD11B1 (0.36) | HSD11B1PDK1PDK2PDE10APKM | |
| SCHEMBL15933175 | 0.73 | HSD11B1 (0.36) | HSD11B1PDK1PDK2PKM | |
| SCHEMBL23097407 | 0.72 | KCNJ6 (0.38) | HSD11B1PDK2PDE10APKMCHRM4 | |
| SCHEMBL25790649 | 0.72 | ATR (0.35) | PDE10ACHRM4 | |
| SCHEMBL17194138 | 0.71 | NTRK1 (0.36) | PDK2NTRK1 | |
| SCHEMBL3825587 | 0.70 | LMNA (0.40) | HSD11B1PDK1PDK2PDE10APKM | |
| SCHEMBL3070206 | 0.70 | LMNA (0.46) | NTRK1 | |
| SCHEMBL24391078 | 0.69 | GABBR2 (0.51) | PDE10ACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125928-A1 | MENIN INHIBITOR AND USE THEREOF | 成都先导药物开发股份有限公司 | 2023-07-06 | — | — | WO | disclosed |