Acrylamide

Acrylamide

SCHEMBL28026684

C=CC(=O)Oc1c(F)c(F)c(F)c(F)c1F.C=CC(N)=O

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 1/20 0.44
FGFR4 P22455 1/20 0.44
THRB P10828 3/20 0.36
HSD17B10 Q99714 1/20 0.32
HPGD P15428 1/20 0.31
THRA P10827 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225748 0.92 THRB (0.40) TSHRALDH1A1THRBHSD17B10HPGD
SCHEMBL2579041 0.89 THRB (0.41) TSHRALDH1A1THRBHSD17B10HPGD
SCHEMBL6433342 0.84 THRB (0.36) TSHRTHRBHPGDTHRA
SCHEMBL1098070 0.83 THRB (0.38) TSHRALDH1A1THRBHSD17B10HPGD
SCHEMBL26688609 0.82 THRB (0.35) TSHRTHRB
SCHEMBL26363017 0.82 THRB (0.35) TSHRTHRB
SCHEMBL6436744 0.81 THRB (0.34) TSHRTHRB
SCHEMBL8737374 0.81 THRB (0.34) THRB
SCHEMBL8733951 0.80 THRB (0.36) TSHRTHRBHPGDTHRA
SCHEMBL6440095 0.80 THRB (0.33) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105189583-A Surface Oxidation of Chelated Biomolecules and Related Methods NVS TECHNOLOGIES INC 2015-12-23 CN disclosed